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Publications
This page provides a list of mitochondrial transplant papers authored/co-authored by the NFRF-T MitoRevolution team members.
Bridging the gap between in vitro and in vivo models: a way forward to clinical translation of mitochondrial transplantation in acute disease states
David F. Bodenstein, Gabriel Siebiger, Yimu Zh, Aaron J. Clasky, Avinash N. Mukkala, Erika L. Beroncal, Lauren Banh, Lili Aslostovar, Sonya Brijbassi, Sarah E. Hogan, James D. McCully, Mohadeseh Mehrabian, Thomas H. Petersen, Lisa A. Robinson, Melanie Walker, Constantine Zachos, MITO2i-MbD Mitochondrial Transplant Consortium, Sowmya Viswanathan, Frank X. Gu, Ori D. Rotstein, Marcelo Cypel, Milica Radisic, Ana C. Andreazza
Normothermic Ex Vivo Kidney Perfusion Improves Early DCD Graft Function Compared With Hypothermic Machine Perfusion and Static Cold Storage
Peter Urbanellis, BSc, MSc, MD, Matyas Hamar, MD, J. Moritz Kaths, MSc, MD, Dagmar Kollmann, MD, PhD, Ivan Linares, MD, PhD, Laura Mazilescu, MD, Sujani Ganesh, MSc, Aryn Wiebe, BSc, Paul M. Yip, PhD, Rohan John, MD, Ana Konvalinka, MD, PhD, Istvan Mucsi, MD, PhD, Anand Ghanekar, MD, PhD, Darius J. Bagli, MD, Lisa A. Robinson, MD, and Markus Selzner, MD
Static lung storage at 10°C maintains mitochondrial health and preserves donor organ function
Aadil Ali, Aizhou Wang, Rafaela V. P. Ribeiro, Erika L. Beroncal, Cristina Baciu, Marcos Galasso, Bruno Gomes, Andrea Mariscal, Olivia Hough, Edson Brambate, Etienne Abdelnour-Berchtold, Vinicius Michaelsen, Yu Zhang, Anajara Gazzalle, Eddy Fan, Laurent Brochard, Jonathan Yeung, Tom Waddell, Mingyao Liu, Ana C. Andreazza, Shaf Keshavjee, Marcelo Cypel
Characterization of mitochondrial health from human peripheral blood mononuclear cells to cerebral organoids derived from induced pluripotent stem cells
Angela Duong, Alesya Evstratova, Adam Sivitilli, J. Javier Hernandez, JessicaGosio, AziziaWahedi, Neal Sondheimer, Jeff L. Wrana, Jean‑Martin Beaulieu, LilianaAttisano & Ana C. Andreazza
Prolonged warm ischemia time leads to severe renal dysfunction of donation‑after‑cardiac death kidney grafts
Peter Urbanellis, Laura Mazilescu, Dagmar Kollmann, Ivan Linares‑Cervantes, J. Moritz Kaths, SujaniGanesh, Fabiola Oquendo, Manraj Sharma, ToruGoto, Yuki Noguchi, Rohan John, Ana Konvalinka, Istvan Mucsi, AnandGhanekar, Darius Bagli, LisaA. Robinson & Markus Selzner
Prolonged Normothermic Ex Vivo Kidney Perfusion Is Superior to Cold Nonoxygenated and Oxygenated Machine Perfusion for the Preservation of DCD Porcine Kidney Grafts
Laura I. Mazilescu, Peter Urbanellis, Moritz J. Kaths, Sujani Ganesh, Toru Goto, Yuki Noguchi, Rohan John, Ana Konvalinka, Istvan Mucsi, Anand Ghanekar, Darius J. Bagli, Julie Turgeon, Annie Karakeusian Rimbaud, Marie-Josée Hébert, Mélanie Dieudé, Isabelle Alleys, Etienne Dore, Eric Boilard, Herman S. Overkleeft, Lianne I. Willems, Lisa A. Robinson, and Markus Selzner
Transcriptome Analysis of Kidney Grafts Subjected to Normothermic Ex Vivo Perfusion Demonstrates an Enrichment of Mitochondrial Metabolism Genes
Peter Urbanellis, Caitriona M. McEvoy, Marko Škrtić, J. Moritz Kaths, Dagmar Kollmann, Ivan Linares, Sujani Ganesh, Fabiola Oquendo, Manraj Sharma, Laura Mazilescu, Toru Goto, Yuki Noguchi, Rohan John, Istvan Mucsi, Anand Ghanekar, Darius Bagli, Ana Konvalinka, Markus Selzner, Lisa A. Robinson
Normothermic Ex-vivo Kidney Perfusion in a Porcine Auto-Transplantation Model Preserves the Expression of Key Mitochondrial Proteins: An Unbiased Proteomics Analysis
Caitriona M. McEvoy, Sergi Clotet-Freixas, Tomas Tokar, Chiara Pastrello, Shelby Reid, Ihor Batruch, Adrien A. E. RaoPeters, J. Moritz Kaths, Peter Urbanellis, Sofia Farkona, Julie A. D. Van, Bradley L. Urquhart, Rohan John, Igor Jurisica, Lisa A. Robinson, Markus Selzner, and Ana Konvalinka
Machine learning directed drug formulation development
Bannigan P, Aldeghi M, Bao Z, Häse F, Aspuru-Guzik A, Allen C.
Evaluation of 10ËšC as the optimal storage temperature for aspiration-injured donor lungs in a large animal transplant model
Etienne Abdelnour-Berchtold, Aadil Ali, Cristina Baciu, Erika L. Beroncal, Aizhou Wang, Olivia Hough, Mitsuaki Kawashima, Manyin Chen, Yu Zhang, Mingyao Liu, Tom Waddell, Ana C. Andreazza, Shaf Keshavjee, and Marcelo Cypel
Successful 3-day lung preservation using a cyclic normothermic ex vivo lung perfusion strategy
Aadil Ali, Antti I. Nykanen, Erika Beroncal, Edson Brambate, Andrea Mariscal, Vinicius Michaelsen, Aizhou Wang, Mitsuaki Kawashima, Rafaela V.P. Ribeiro, Yu Zhang, Eddy Fan, Laurent Brochard, Jonathan Yeung, Tom Waddell, Mingyao Liu, Ana C. Andreazza, Shaf Keshavjee,and Marcelo Cypel
Normothermic Ex Vivo Kidney Perfusion for Human Kidney Transplantation: First North American Results
Mazilescu LI, Urbanellis P, Kim SJ, Goto T, Noguchi Y, Konvalinka A, Reichman TW, Sayed BA, Mucsi I, Lee JY, Robinson LA, Ghanekar A, Selzner M.
Optimization of differential filtration‑based mitochondrial isolation for mitochondrial transplant to cerebral organoids
Bodenstein DF, Powlowski P, Zachos KA, El Soufi El Sabbagh D, Jeong H, Attisano L, Edgar L, Wallace DC, Andreazza AC.
Augmented Parkin-dependent mitophagy underlies the hepatoprotective effect of remote ischemic conditioning used prior to hemorrhagic shock
Naraiah Mukkala A, Petrut R, Goldfarb R, Leigh Beroncal E, Ho Leung C, Khan Z, Ailenberg M, Jerkic M, Andreazza AC, Rhind SG, Jeschke MG, Kapus A, Rotstein OD.
Machine learning models to accelerate the design of polymeric long-acting injectables
Bannigan P, Bao Z, Hickman RJ, Aldeghi M, Häse F, Aspuru-Guzik A, Allen C.
Normothermic ex vivo kidney perfusion preserves mitochondrial and graft function after warm ischemia and is further enhanced by AP39
Kawamura M, Parmentier C, Ray S, Clotet-Freixas S, Leung S, John R, Mazilescu L, Nogueira E, Noguchi Y, Goto T, Arulratnam B, Ganesh S, Tamang T, Lees K, Reichman TW, Andreazza AC, Kim PK, Konvalinka A, Selzner M, Robinson LA.
Primitive macrophages enable long-term vascularization of human heart-on-a-chip platforms
Landau S, Zhao Y, Hamidzada H, Kent GM, Okhovatian S, Lu RXZ, Liu C, Wagner KT, Cheung K, Shawky SA, Vosoughi D, Beroncal EL, Fernandes I, Cummins CL, Andreazza AC, Keller GM, Epelman S, Radisic M.
Primitive macrophages induce sarcomeric maturation and functional enhancement of developing human cardiac microtissues via efferocytic pathways
Hamidzada H, Pascual-Gil S, Wu Q, Kent GM, Massé S, Kantores C, Kuzmanov U, Gomez-Garcia MJ, Rafatian N, Gorman RA, Wauchop M, Chen W, Landau S, Subha T, Atkins MH, Zhao Y, Beroncal E, Fernandes I, Nanthakumar J, Vohra S, Wang EY, Sadikov TV, Razani B, McGaha TL, Andreazza AC, Gramolini A, Backx PH, Nanthakumar K, Laflamme MA, Keller G, Radisic M, Epelman S.
Cardiac tissue model of immune-induced dysfunction reveals the role of free mitochondrial DNA and the therapeutic effects of exosomes
Lu RXZ, Rafatian N, Zhao Y, Wagner KT, Beroncal EL, Li B, Lee C, Chen J, Churcher E, Vosoughi D, Liu C, Wang Y, Baker A, Trahtemberg U, Li B, Pierro A, Andreazza AC, Dos Santos CC, Radisic M.
Combining Oxygenated Cold Perfusion With Normothermic Ex Vivo Perfusion Improves the Outcome of Donation After Circulatory Death Porcine Kidney Transplantation
Mazilescu LI, Goto T, John R, Rosales R, Ganesh S, Yu F, Noguchi Y, Kawamura M, Dezard V, Gao F, Urbanellis P, Parmentier C, Konvalinka A, Bagli DJ, Reichman TW, Robinson LA, Selzner M.
Optimizing lipid nanoparticles for fetal gene delivery in vitro, ex vivo, and
aided with machine learning
Abostait A, Abdelkarim M, Bao Z, Miyake Y, Tse WH, Di Ciano-Oliveir C, Buerki-Thurnherr T, Allen C, Keijzer R, Labouta HI.
Evaluating the corporate social responsibility agenda for high‑cost novel therapies: roles for government and civil society
Anna Wong, Gul Saeed, Sarah Garner and Jillian Kohler
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